The Medicinal Chemistry Section of the Institute is responsible for the design and synthesis of chemical compounds which are then evaluated for their biological activity and pharmacokinetic profile.
The section comprises a variety of expertise ranging from computer modelling to small and large scale synthesis. Our scientists use their expertise and the latest techniques to synthesise both individual as well as libraries of compounds for biological screening.
The medicinal chemistry section comprises:
- 20 fumehoods across two chemistry laboratories, as well as additional space comprising two preparation rooms, a store room, write up area and offices
- Access to all analytical instruments required for synthetic chemistry including an automated 400 MHz NMR for routine work and a 600 MHz NMR, facility for single crystal structure determination, mass spectrometers for low and high resolution mass determination as well as a ToF-MS, analytical and preparative HPLC, dedicated LC-MS and GC-MS, polarimeter, IR spectrometer, etc
- CambridgeSoft's Electronic Lab Notebooks
- Access to state-of-the-art computing facilities including the Schrodinger software package for computational chemistry and molecular modelling
The research of the section is supported by PhD students, post-doctoral research assistants, MSc and MChem undergraduate project students. We annually welcome chemistry summer students from ESCOM (France), and frequently have study leave undergraduates from other UK universities including Oxford and Leeds, University of Clermont-Ferrand (France) and the University of Lisbon (Portugal).
We also offer our research expertise to industry details of which can be viewed here.