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Dr Chaitrali Kulkarni

PositionPostdoctoral Research Assistant
Location3.16 Norcroft building
DepartmentBradford School of Pharmacy
RKT CentrePharmaceutical Engineering
Telephone+44 (0) 1274 236110
EmailC.Kulkarni1@bradford.ac.uk

Research Interests (key words only)

Extrusion processing, co-crystals, polymorphs, solid dispersions

Biography

Chaitrali has been awarded PhD in Pharmaceutics from the Centre for Pharmaceutical Engineering Science, University of Bradford. Her PhD research involves novel formulations of poorly soluble drugs using extrusion process. Her objective was to understand extrusion processing and explore its novel pharmaceutical applications.

She joined the Centre for Pharmaceutical Engineering Science as a Postdoctoral Research Assistant. She is responsible for developing and conducting a range of laboratory-based activities to support a EPSRC funded research project 'A Novel Continuous Method for Co-crystal Formation' in the area of crystallisation, hot melt extrusion, and Process Analytical Technology (PAT).

The aim of her research is to explore the underpinning science behind the formation of co-crystals using melt extrusion processing using variety of process engineering and process analytical technologies mainly NIR, Raman spectroscopy and X-ray techniques. The time resolved nature of the crystallisation will be studied utilising combine SAXS/WAXS at beamlines.

Study History

  • Bachelor of Pharmacy: Bharati Vidyapeeth College of Pharmacy, Kolhapur. 2007
  • M. Res. Applied Science: Nottingham Trent University. 2008
  • PhD: Bradford University. 2014

Research Areas

Extrusion processing, crystal engineering, solid dispersions

Current Projects

EPSRC funded research project 'A Novel Continuous Method for Co-crystal Formation.'

Publications

Chaitrali Kulkarni, Adrian Kelly, Tim Gough, Anant Paradkar, Technology for obtaining stabilized metastable polymorph. Patent application number: GB 1208489.3

Chaitrali Kulkarni, John Kendrick, Adrian Kelly, Tim Gough, RC Dash, Anant Paradkar, Solid state polymorphic transformation of artemisinin in high temperature extrusion technique, CrystEngComm. 2013, 15, 6297-6300

Chaitrali Kulkarni, Adrian Kelly, John Kendick, Tim Gough, Anant Paradkar, Mechanism of polymorphic transformation of artemisinin during high temperature extrusion process, Crystal Growth & Design 2013, 13, 5157−5161

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