Dr Jim Boyne
|Position||Lecturer in Molecular and Cellular Biology|
|Location||Room H38C, Richmond Building|
|Department||School of Chemistry and Bioscience|
|RKT Centre||Centre for Skin Sciences|
Research Interests (key words only)
RNA, Cancer, Viruses
Teaching and Supervisory Responsibilities
- Responsible for teaching Molecular Biology and Genetics at all levels
- Bradford GMO committee
- PhD – University of Sheffield (2002) - “Molecular mechanisms that control eukaryotic cell division”
- BSc (Hons) in Genetics (2i) – University of Sheffield (1996)
- Senior Post-doctoral research assistant at Institute of Molecular and Cellular Biology, University of Leeds (2004-2009).
- Post-doctoral research assistant at Leeds Institute of Molecular Medicine (2001-2004).
- Research scientist at Sheffield Diagnostic Genetics Service, Sheffield Children’s Hospital (1997-1998)
Dr Boyne is an early career research scientist who is in the process of establishing a melanoma research group at the University of Bradford. Prior to his appointment as lecturer, Dr Boyne held post-doctoral and senior post-doctoral positions at the Leeds Institute of Molecular Medicine (LIMM) and University of Leeds, which resulted in a number of published articles in high impact-factor journals such as EMBOJ and PNAS (the current H-index for JR Boyne is 12). Dr Boyne has a strong background in the molecular biology of cancer in addition to RNA processing and virology.
- Prof. Newton-Bishop (LIMM)
- Prof. Whitehouse (University of Leeds)
- Prof. Reed (Harvard University)
- Jackson, B.R., Boyne, J.R., Noerenberg, M., Taylor, A., Hautbergue, G.M., Walsh, M.J., Wheat, R., Blackbourn, D.J., Wilson, S.A., and Whitehouse, A. (2011). An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export. PLoS Pathog 7, e1002138.
- Boyne, J.R., Jackson, B.R., Taylor, A., Macnab, S.A., and Whitehouse, A. (2010a). Kaposi's sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs. EMBO J 29, 1851-1864.
- Boyne, J.R., Jackson, B.R., and Whitehouse, A. (2010b). ORF57: Master regulator of KSHV mRNA biogenesis. Cell Cycle 9, 2702-2703.
- Boyne, J.R., and Whitehouse, A. (2009). Nucleolar disruption impairs Kaposi's sarcoma-associated herpesvirus ORF57-mediated nuclear export of intronless viral mRNAs. FEBS Lett 583, 3549-3556.
- Colgan, K.J., Boyne, J.R., and Whitehouse, A. (2009a). Identification of a response element in a herpesvirus saimiri mRNA recognized by the ORF57 protein. J Gen Virol 90, 596-601.
- Colgan, K.J., Boyne, J.R., and Whitehouse, A. (2009b). Uncoupling of hTREX demonstrates that UAP56 and hTHO-complex recruitment onto herpesvirus saimiri intronless transcripts is required for replication. J Gen Virol 90, 1455-1460.
- Boyne, J.R., Colgan, K.J., and Whitehouse, A. (2008a). Herpesvirus saimiri ORF57: a post-transcriptional regulatory protein. Front Biosci 13, 2928-2938.
- Boyne, J.R., Colgan, K.J., and Whitehouse, A. (2008b). Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication. PLoS Pathog 4, e1000194.
- Corbett, M., Xiong, Y., Boyne, J.R., Wright, D.J., Munro, E., and Price, C. (2006). IQGAP and mitotic exit network (MEN) proteins are required for cytokinesis and re-polarization of the acting cytoskeleton in the budding yeast, Saccharomyces cerevisiae. Eur J Cell Biol 85, 1201-1215.
- Boyne, J.R., and Whitehouse, A. (2006a). gamma-2 Herpes virus post-transcriptional gene regulation. Clin Microbiol Infect 12, 110-117.
- Boyne, J.R., and Whitehouse, A. (2006b). Nucleolar trafficking is essential for nuclear export of intronless herpesvirus mRNA. Proc Natl Acad Sci U S A 103, 15190-15195.
In the News/Media
- Dr Jim Boyne tells us his teaching and research in genetics, British Science Festival, September 2011