Dr Chaitrali Kulkarni
|Position||Postdoctoral Research Assistant|
|Location||3.16 Norcroft building|
|Department||Bradford School of Pharmacy|
|RKT Centre||Pharmaceutical Engineering|
|Telephone||+44 (0) 1274 236110|
Research Interests (key words only)
Extrusion processing, co-crystals, polymorphs, solid dispersions
Chaitrali has been awarded PhD in Pharmaceutics from the Centre for Pharmaceutical Engineering Science, University of Bradford. Her PhD research involves novel formulations of poorly soluble drugs using extrusion process. Her objective was to understand extrusion processing and explore its novel pharmaceutical applications.
She joined the Centre for Pharmaceutical Engineering Science as a Postdoctoral Research Assistant. She is responsible for developing and conducting a range of laboratory-based activities to support a EPSRC funded research project 'A Novel Continuous Method for Co-crystal Formation' in the area of crystallisation, hot melt extrusion, and Process Analytical Technology (PAT).
The aim of her research is to explore the underpinning science behind the formation of co-crystals using melt extrusion processing using variety of process engineering and process analytical technologies mainly NIR, Raman spectroscopy and X-ray techniques. The time resolved nature of the crystallisation will be studied utilising combine SAXS/WAXS at beamlines.
- Bachelor of Pharmacy: Bharati Vidyapeeth College of Pharmacy, Kolhapur. 2007
- M. Res. Applied Science: Nottingham Trent University. 2008
- PhD: Bradford University. 2014
Extrusion processing, crystal engineering, solid dispersions
EPSRC funded research project 'A Novel Continuous Method for Co-crystal Formation.'
Chaitrali Kulkarni, Adrian Kelly, Tim Gough, Anant Paradkar, Technology for obtaining stabilized metastable polymorph. Patent application number: GB 1208489.3
Chaitrali Kulkarni, John Kendrick, Adrian Kelly, Tim Gough, RC Dash, Anant Paradkar, Solid state polymorphic transformation of artemisinin in high temperature extrusion technique, CrystEngComm. 2013, 15, 6297-6300
Chaitrali Kulkarni, Adrian Kelly, John Kendick, Tim Gough, Anant Paradkar, Mechanism of polymorphic transformation of artemisinin during high temperature extrusion process, Crystal Growth & Design 2013, 13, 5157−5161