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Dr Khaled H Assi

PositionSenior Lecturer in Pharmaceutical Sciences
LocationL26B
DepartmentSchool of Pharmacy
Telephone+ 44 (0) 1274 234703
EmailK.H.A.Assi@bradford.ac.uk

Research Interests (key words only)

Formulation for Dry powder inhalers; urinary drug excretion to identify lung and systemic deposition following inhalation; bioequivalence of inhaled drugs and inhalation techniques; determination of the in-vitro characteristics of inhaled products and assessing the in-vitro quality of the dose emitted from inhalation systems; development of pharmaceutical and bioanalytical assay methods for determination of inhaled drugs and its metabolites in aqueous and biological fluids for bioequivalence and pharmacokinetic studies

Teaching and Supervisory Responsibilities

  • Medicines and Quality Assurance  (PH5003D) —MSc course: Module Leader
  • Pharmaceutical Analysis and Quality Assurance (PH 4030D): Module Leader
  • Drug Regulation and Quality Assurance (PH8010M)
  • Assessing the Quality of Medicines (PH1008M): Module Leader
  • Communication Skills (PH1011)          

Administrative Responsibilities

  • Year1 phase tutor for BSc Pharmaceutical Management Course (2009-to date)
  • Team member of the Course Management Committee for Pharmaceutical Management course
  • IPI Safety Liaison officer (2004-2006)
  • Member of the Health and Safety Committee of the Faculty of Life Sciences, University of Bradford (2004-2006)
  • Personal tutor: currently have 27 tutees from both Pharmacy and Pharmaceutical management courses

Biography

Dr Khaled H Assi obtained his BSc in the Sciences of Chemistry in 1994 and was awarded the PhD in pharmaceutical analysis by the University of Bradford, in 1999.

He then took up a post doctoral post at university of Bradford between 1999-2001 working on the inhaled therapies.  His post doctoral program was extended for one more year through an awarded grant from Glaxo SmithKline joint with Professor H Chrystyn .

In 2002, he was accepted a research fellowship at Bradford School of Pharmacy. Dr Assi was appointed as a Lecturer at the Bradford School of Pharmacy, in July 2004 and has continued developing his research in the inhaled therapies area. In this position he is teaching the pharmacy and pharmaceutical management students at different levels.  The modules he delivers cover the area of pharmaceutical analysis, Quality assurance and quality control of pharmaceuticals.

He is also active in the research. His research interests cover the inhalation therapies and developing of pharmaceutical and bioanalytical assay methods for the determination of inhaled drugs in biological fluids to measure the lung deposition.

He has published over 35 Conference and Journal papers. He supervised 4completed PhD projects and currently supervising 2 PhD students. He was an internal examiner for many PhD theses and also he is a reviewer for several international journals

Publications

Abdelrahim, M.E., Assi, K.H. and Chrystyn, Henry (2011) Dose emission and aerodynamic characterization of the terbutaline sulphate dose emitted from a Turbuhaler at low inhalation flow. Pharmaceutical Development and Technology. ISSN 1083-7450 (In Press)

M. S. Althanyan, K.H. Assi, B.J. Clark, J. Hanaee“Microemulsion high performance liquid chromatography (MELC) method for the determination of terbutaline in pharmaceutical preparation”, J. Phar. Biomed. Anal; 55(2011) 397-402.

Abdelrahim, Mohamed E., Assi, Khaled H. and Chrystyn, Henry (2011) “Relative bioavailability of terbutaline to the lung following inhalation, using urinary excretion”,. British Journal of Clinical Pharmacology, 71 (4). pp. 608-610. ISSN 1365-2125

D.K. Nadarassan, H Chrystyn, BJ Clark, KH Assi “Aerodynamic characteristics of a dry powder inhaler at low inhalation flows using a mixing inlet with an Andersen Cascade Impactor”, European Journal of Pharmaceutical Sciences 39 (2010) 348–354.

Alaboud, A., Assi, K.H. and Chrystyn, Henry (2010) “In vitro characterization of the emitted dose from the foradil aerolizer to identify the influence of inhalation flow, inhilation volume and the number of inhalations per dose”,. Respiratory drug delivery, 3. pp. 803-806.

Mashat M, Clark BJ, Chrystyn H, Assi KH “Development and validation of HPLC method for the determination of tobramycin in urine samples post-inhalation using pre-column derivatisation with fluorescein isothiocyanate”, Journal of Chromatography B, 869 (2008) 59-66.

 

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