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Latest Publications

CSS staff in bold 


2017

Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep 1;13(9):e1006966. doi: 10.1371/journal.pgen.1006966. eCollection 2017 Sep. PubMed PMID: 28863138.

Weiland D, Brachvogel B, Hornig-Do HT, Neuhaus JFG, Holzer T, Tobin DJ, Niessen CM, Wiesner RJ, Baris OR. Imbalance of Mitochondrial Respiratory Chain Complexes in the Epidermis Induces Severe Skin Inflammation. J Invest Dermatol. 2017 Aug 31. pii: S0022-202X(17)32834-8. doi: 10.1016/j.jid.2017.08.019. [Epub ahead of print] PubMed PMID: 28867657.

Tobin DJ. Introduction to skin aging. J Tissue Viability. 2017 Feb;26(1):37-46. doi: 10.1016/j.jtv.2016.03.002. Epub 2016 Mar 14. PubMed PMID:27020864.

Botchkarev VA. Second International Symposium-Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases. J Invest Dermatol. 2017 Aug;137(8):1604-1608. doi: 10.1016/j.jid.2017.01.037. Epub 2017 Jun 2. PubMed PMID: 28583676.

Messenger AG, Botchkareva NV. Unraveling the secret life of the hair follicle: from fungi to innovative hair loss therapies. Exp Dermatol. 2017 Jun;26(6):471. doi: 10.1111/exd.13384. PubMed PMID: 28608517.

Westgate GE, Ginger RS, Green MR. The biology and genetics of curly hair. Exp Dermatol. 2017;26:483–490. https://doi.org/10.1111/exd.13347

Singh SK, Baker R, Sikkink SK, Nizard C, Schnebert S, Kurfurst R, Tobin DJ. E-Cadherin mediates UVR- and calcium-induced melanin transfer in human skin cells. Exp Dermatol. 2017 Jun 21. doi: 10.1111/exd.13395. [Epub ahead of print] PubMed PMID: 28636748.

Sonthalia S, Priya A, Tobin DJ. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases. Indian J Dermatol. 2017 May-Jun;62(3):304-308. doi: 10.4103/ijd.IJD_221_17. PubMed PMID: 28584374; PubMed Central PMCID: PMC5448266.

Botchkareva NV. The Molecular Revolution in Cutaneous Biology: Noncoding RNAs: New Molecular Players in Dermatology and Cutaneous Biology. J Invest Dermatol. 2017 May;137(5):e105-e111. doi: 10.1016/j.jid.2017.02.001. Review. PubMed PMID:28411840.

Mignon C, Uzunbajakava NE, Raafs B, Botchkareva NV, Tobin DJ. Photobiomodulation of human dermal fibroblasts in vitro: decisive role of cell culture conditions and treatment protocols on experimental outcome. Sci Rep. 2017 Jun 5;7(1):2797. doi: 10.1038/s41598-017-02802-0. PubMed PMID: 28584230; PubMed Central PMCID: PMC5459822.

Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A. p63 transcription factor regulates nuclear shape and expression of nuclear envelope-associated genes in epidermal keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 doi:10.1016/j.jid.2017.05.013. Epub 2017 Jun 6. PubMed PMID: 28595999; PubMed Central
PMCID: PMC5610935.

Botchkarev VA. Second International Symposium-Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases. J Invest Dermatol. 2017 Aug;137(8):1604-1608. doi: 10.1016/j.jid.2017.01.037. Epub 2017 Jun 2. PubMed PMID: 28583676.

Botchkarev VA. The Molecular Revolution in Cutaneous Biology: Chromosomal Territories, Higher-Order Chromatin Remodeling, and the Control of Gene Expression in Keratinocytes. J Invest Dermatol. 2017 May;137(5):e93-e99. doi:10.1016/j.jid.2016.04.040. Review. PubMed PMID: 28411854.

Aunin E, Broadley D, Ahmed MI, Mardaryev AN, Botchkareva NV. Exploring a Role for Regulatory miRNAs In Wound Healing during Ageing:Involvement of miR-200c in
wound repair. Sci Rep. 2017 Jun 12;7(1):3257. doi: 10.1038/s41598-017-03331-6. PubMed PMID: 28607463; PubMed Central PMCID: PMC5468284.

Buscone S, Mardaryev AN, Raafs B, Bikker JW, Sticht C, Gretz N, Farjo N, Uzunbajakava NE, Botchkareva NV. A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle. Lasers Surg Med. 2017 Apr 18. doi: 10.1002/lsm.22673. [Epub ahead of print] PubMed PMID:
28418107.

 

2016

Botchkarev VA, Mardaryev AN. Repressing the Keratinocyte Genome: How the Polycomb Complex Subunits Operate in Concert to Control Skin and Hair Follicle Development. J Invest Dermatol. 2016 Aug;136(8):1538-40. doi:10.1016/j.jid.2016.04.026. PubMed PMID: 27450498.

Westgate GE. In search of hair damage using metabolomics? Exp Dermatol. 2016 Jun 16. doi: 10.1111/exd.13117. [Epub ahead of print] PubMed PMID: 27306139.

Botchkarev VA, Sharov AA. Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality. J Invest Dermatol. 2016 Mar;136(3):557-9. doi: 10.1016/j.jid.2015.10.068. PubMed PMID: 26902124.

Botchkarev VA. Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Nov;17(2):30-2. doi: 10.1038/jidsymp.2015.37. Review.PubMed PMID: 26551942; PubMed Central PMCID: PMC5080658.

A.N. Mardaryev, B. Liu, V. Rapisarda, K. Poterlowicz, I. Malaschuk, J. Rudolf, A.A.Sharov, C.A. Jahoda, M.Y. Fessing, S.A. Benitah, G.L. Xu, V.A. Botchkarev Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium J of Cell Biology, 2016, 212, 77-89

Noordam R, Gunn DA, van Drielen K, Westgate G, Slagboom PE, de Craen AJ, van Heemst D. Low circulating insulin-like growth factor-1 and high density lipoprotein are associated with hair loss in middle-aged women. Br J Dermatol. 2016 Mar 9. doi: 10.1111/bjd.14529. [Epub ahead of print] PubMed PMID: 26959288.

Mignon C, Botchkareva NV, Uzunbajakava NE, Tobin DJ. Photobiomodulation for hair regrowth and wound healing: a therapy full of promise but a literature full of confusion.  Dermatol. 2016 Apr 20. doi: 10.1111/exd.13035. [Epub ahead of print] PubMed PMID: 27095546. http://www.ncbi.nlm.nih.gov/pubmed/27095546

Tobin DJ. Introduction to skin aging. J Tissue Viability. 2016 Mar 14. pii:S0965-206X(16)00028-0. doi: 10.1016/j.jtv.2016.03.002. [Epub ahead of print]
PubMed PMID: 27020864.

Joly-Tonetti N, Wibawa JI, Bell M, Tobin D. Melanin fate in the human epidermis: a reassessment of how best to detect and analyse histologically. Exp
Dermatol. 2016 Jul;25(7):501-4. doi: 10.1111/exd.13016. Review. PubMed PMID:26998907.

Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacón-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuña-Alonzo V, Jaramillo C, Arias W, Barquera Lozano R, Macín Pérez G, Gómez-Valdés J, Villamil-Ramírez H, Hunemeier T, Ramallo V, Silva de Cerqueira CC, Hurtado M, Villegas V, Granja V, Gallo C, Poletti G, Schuler-Faccini L, Salzano FM, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, Gonzalez-José R, Headon D, López-Otín C, Tobin DJ, Balding D, Ruiz-Linares A. A genome-wide association scan in admixed Latin Americans identifies loci influencing facial and scalp hair features. Nat Commun. 2016 Mar 7:10815. doi:10.1038/ncomms10815. PubMed PMID: 26926045; PubMed Central PMCID: PMC4773514.

Thornton MJ. Human skin: a mirror for estrogen action? Menopause. 2016 Feb;23(2):119-20. doi: 10.1097/GME.0000000000000589. PubMed PMID: 26757275.

Journal Articles (2009 - 2015)

CSS staff in bold     2009 Papers   2010 Papers   2011 Papers   2012 Papers   2013 papers  Books


2015

Botchkarev VA. Epigenetic Regulation of Epidermal Development and Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Jul;17(1):18-9. doi: 10.1038/jidsymp.2015.15. PubMed PMID: 26067308.

Seltmann J, Roesner LM, von Hesler FW, Wittmann M, Werfel T. IL-33 impacts on the skin barrier by downregulating the  expression of filaggrin. J Allergy Clin Immunol. 2015 Apr 9. pii: S0091-6749(15)00335-8. doi: 10.1016/j.jaci.2015.01.048. [Epub ahead of print] PubMed PMID: 25863977.

Kendall AC, Pilkington SM, Massey KA, Sassano G, Rhodes LE, Nicolaou A. Distribution of Bioactive Lipid Mediators in Human Skin. J Invest Dermatol. 2015 Feb 10. doi: 10.1038/jid.2015.41. [Epub ahead of print] PubMed PMID: 25668241.

D'Erme AM, Wilsmann-Theis D, Wagenpfeil J, Hölzel M, Ferring-Schmitt S, Sternberg S, Wittmann M, Peters B, Bosio A, Bieber T, Wenzel J. IL-36γ (IL-1F9) Is a Biomarker for Psoriasis Skin Lesions. J Invest Dermatol. 2015 Apr;135(4):1025-32. doi: 10.1038/jid.2014.532. Epub 2014 Dec 19. PubMed PMID:25525775.

Pomari E, Dalla Valle L, Pertile P, Colombo L, Thornton MJ. Intracrine sex steroid synthesis and signaling in human epidermal keratinocytes and dermal fibroblasts. FASEB J. 2015 Feb;29(2):508-24. doi: 10.1096/fj.14-251363. Epub 2014 Nov 12. PubMed PMID: 25392269. http://www.fasebj.org/content/early/2014/11/12/fj.14-251363.long

Kloepper JE, Baris OR, Reuter K, Kobayashi K, Weiland D, Vidali S, Tobin DJ, Niemann C, Wiesner RJ, Paus R. Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions. J Invest Dermatol. 2015 Mar;135(3):679-89. doi:10.1038/jid.2014.475. Epub 2014 Nov 5. PubMed PMID: 25371971.

Hardman JA, Tobin DJ, Haslam IS, Farjo N, Farjo B, Al-Nuaimi Y, Grimaldi B, Paus R. The peripheral clock regulates human pigmentation. J Invest Dermatol. 2015 Apr;135(4):1053-64. doi: 10.1038/jid.2014.442. Epub 2014 Oct 13. PubMed PMID: 25310406. http://www.nature.com/jid/journal/vaop/ncurrent/pdf/jid2014442a.pdf

Botchkarev VA. Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Nov;17(2):30-2. doi: 10.1038/jidsymp.2015.37. Review. PubMed PMID: 26551942.

Tobin DJ. Age-related hair pigment loss. Curr Probl Dermatol. 2015;47:128-38. doi: 10.1159/000369413. Epub 2015 Feb 20. Review. PubMed PMID: 26370651.

Alase AA, El-Sherbiny YM, Vital EM, Tobin DJ, Turner NA, Wittmann M. IFNλ Stimulates MxA Production in Human Dermal Fibroblasts via a MAPK-Dependent STAT1-Independent Mechanism. J Invest Dermatol. 2015 Dec;135(12):2935-43. doi:10.1038/jid.2015.317. Epub 2015 Aug 19. PubMed PMID: 26288353.

Zhang CF, Gruber F, Ni C, Mildner M, Koenig U, Karner S, Barresi C, Rossiter H, Narzt MS, Nagelreiter IM, Larue L, Tobin DJ, Eckhart L, Tschachler E. Suppression of autophagy dysregulates the antioxidant response and causes premature senescence of melanocytes. J Invest Dermatol. 2015 May;135(5):1348-57. doi: 10.1038/jid.2014.439. Epub 2014 Oct 7. PubMed PMID: 25290687. http://www.nature.com/jid/journal/vaop/ncurrent/pdf/jid2014439a.pdf

Grant CA, Twigg PC, Baker R, Tobin DJ. Tattoo ink nanoparticles in skin tissue and fibroblasts. Beilstein J Nanotechnol. 2015 May 20;6:1183-91. doi: 10.3762/bjnano.6.120. eCollection 2015. PubMed PMID: 26171294; PubMed Central PMCID: PMC4464189.

Grant CA, Twigg PC, Tobin DJ. Nano-scale observations of tattoo pigments in skin by atomic force microscopy. Curr Probl Dermatol. 2015;48:97-102. doi:  10.1159/000369187. Epub 2015 Mar 26. PubMed PMID: 25833630.

Andl T, Botchkareva NV. MicroRNAs (miRNAs) in the control of HF development and cycling: the next frontiers in hair research. Exp Dermatol. 2015 Nov;24(11):821-6. doi: 10.1111/exd.12785. Epub 2015 Aug 25. Review. PubMed PMID: 26121602.


2014

Akhbari P, Whitehouse A, Boyne JR. Long non coding RNAs drive metastatic progression in melanoma (Review). Int J Oncol. 2014 Dec;45(6):2181-6. Epub 2014 Oct 1.

Sharova TY, Poterlowicz K, Botchkareva NV, Kondratiev NA, Aziz A, Spiegel JH, Botchkarev VA, Sharov AA. Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy.J Invest Dermatol. 2014 Dec;134(12):2873-82. doi: 10.1038/jid.2014.267. Epub 2014 Jul 7. http://www.nature.com/jid/journal/v134/n12/pdf/jid2014267a.pdf

Ahmed MI, Alam M, Emelianov VU, Poterlowicz K, Patel A, Sharov AA, Mardaryev AN, Botchkareva NV. MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway. J Cell Biol. 2014 Nov 24;207(4):549-67.

Lewis CJ, Mardaryev AN, Sharov AAFessing MYBotchkarev VA. The Epigenetic Regulation of Wound Healing. Adv Wound Care (New Rochelle). 2014 Jul 1;3(7):468-475. Review. (New Journal)

Wittmann M, McGonagle D, Werfel TCytokines as therapeutic targets in skin inflammation. Cytokine Growth Factor Rev. 2014 Aug;25(4):443-51. Review. http://www.sciencedirect.com/science/article/pii/S1359610114000707

Botchkarev VA, Flores ERp53/p63/p73 in the epidermis in health and disease. Cold Spring Harb Perspect Med. 2014 Aug 1;4(8). pii: a015248

Fessing MYGene regulation at a distance: higher-order chromatin folding and the coordinated control of gene transcription at the epidermal differentiation complex locus. J Invest Dermatol. 2014 Sep;134(9):2307-10. http://www.nature.com/jid/journal/v134/n9/pdf/jid2014247a.pdf                                

Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY. p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11. doi: 10.1242/dev.103200. http://www.ncbi.nlm.nih.gov/pubmed/24346698

Pedersen JS, Valen E, Velazquez AM, Parker BJ, Rasmussen M, Lindgreen S, Lilje B, Tobin DJ, Kelly TK, Vang S, Andersson R, Jones PA, Hoover CA, Tikhonov A, Prokhortchouk E, Rubin EM, Sandelin A, Gilbert MT, Krogh A, Willerslev E, Orlando L. Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Res. 2014 Mar;24(3):454-66. http://www.ncbi.nlm.nih.gov/pubmed/24299735

Gruber JV, Holtz R, Sikkink SK, Tobin DJ. In vitro and ex vivo examination of topical Pomiferin treatments. Fitoterapia. 2014 Feb 8. pii: S0367-326X(14)00029-X. doi:  10.1016/j.fitote.2014.01.023. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/24513505

Tobin DJ. Alopecia Areata And Vitiligo - Partners In Crime Or A Case Of False Alibis. Exp Dermatol. 2013 Dec 20. doi: 10.1111/exd.12309. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/24372718

Lewis CJ, Mardaryev AN, Poterlowicz K, Sharova TY, Aziz A, Sharpe DT, Botchkareva NV, Sharov AA. Bone morphogenetic protein signaling suppresses wound-induced skin repair by inhibiting keratinocyte proliferation and migration. J Invest Dermatol. 2014 Mar;134(3):827-37 http://www.ncbi.nlm.nih.gov/pubmed/24126843

Weiß N, Stegemann A, Elsayed MA, Schallreuter KU, Luger TA, Loser K, Metze D, Weishaupt C, Böhm M. Inhibition of the prohormone convertase subtilisin-kexin isoenzyme-1 induces apoptosis in human melanoma cells. J Invest Dermatol. 2014 Jan;134(1):168-75. http://www.ncbi.nlm.nih.gov/pubmed/23884247

 

PATENT

Title: Compositions and methods for modulating skin pigmentation.  Document Type & Number: United States Patent 8883725. Inventors Singh, SK and Tobin, DJ Institution:  University of Bradford.                


(2013)

Top

Rahim RR, Husain A, Tobin DJ, Lawrence CM. Desmoplastic melanoma presenting with localised hair repigmentation. Br J Dermatol. 2013 Jul 20. doi: 10.1111/bjd.12521. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/23869420

Botchkarev VA, Fessing MY, Botchkareva NV, Westgate G, Tobin DJ. First international symposium "epigenetic control of skin development and regeneration": how chromatin regulators orchestrate skin functions. J Invest Dermatol. 2013 Aug;133(8):1918-21. doi: 0.1038/jid.2013.126. http://www.ncbi.nlm.nih.gov/pubmed/23856928

Liu W, Peng Y, Tobin DJ. A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis. PeerJ. 2013 Mar 5;1:e49. doi: 10.7717/peerj.49. Print 2013. http://www.ncbi.nlm.nih.gov/pubmed/23638386

Westgate GE, Botchkareva NV, Tobin DJ. The biology of hair diversity. Int J Cosmet Sci. 2013 Aug;35(4):329-36. Epub 2013 Mar 6. http://www.ncbi.nlm.nih.gov/pubmed/23363384

Samuelov L, Sprecher E, Sugawara K, Singh SK, Tobin DJ, Tsuruta D, Bíró T, Kloepper JE, Paus R. Topobiology of human pigmentation: P-cadherin selectively stimulates hair follicle melanogenesis. J Invest Dermatol. 2013 Jun;133(6):1591-600. Epub 2013 Jan 18. http://www.ncbi.nlm.nih.gov/pubmed/2333434

Singh SK, Baker R, Wibawa JI, Bell M, Tobin DJ. The effects of Sophora angustifolia and other natural plant extracts on melanogenesis and melanin transfer in human skin cells. Exp Dermatol. 2013 Jan;22(1):67-9. http://www.ncbi.nlm.nih.gov/pubmed/23278898

Botchkareva NV. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration. Cell Cycle. 2012 Feb 1;11(3):468-74. doi: 10.4161/cc.11.3.19058. Epub 2012 Feb 1. Review. http://www.ncbi.nlm.nih.gov/pubmed/2226218

Gdula MR, Poterlowicz K, Mardaryev AN, Sharov AA, Peng Y, Fessing MY, Botchkarev VA Remodeling of Three-Dimensional Organization of the Nucleus during Terminal Keratinocyte Differentiation in the EpidermisJ Invest Dermatol. 2013 Feb 13. doi: 10.1038/jid.2013.66. http://www.ncbi.nlm.nih.gov/pubmed/2340740

Paus R, Haslam IS, Sharov AA, Botchkarev VA. Pathobiology of chemotherapy-induced hair loss. Lancet Oncol. 2013 Feb;14(2):e50-9. doi: 10.1016/S1470-2045(12)70553-3. http://www.ncbi.nlm.nih.gov/pubmed/2336968

Liu B, Liu YF, Du YR, Mardaryev AN, Yang W, Chen H, Xu ZM, Xu CQ, Zhang XR, Botchkarev VA, Zhang Y, Xu GL. Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development. 2013 Feb;140(4):780-8. doi: 10.1242/dev.08503. http://www.ncbi.nlm.nih.gov/pubmed/23362346

Kohwi-Shigematsu T, Poterlowicz K, Ordinario E, Han HJ, Botchkarev VA, Kohwi Y. Genome organizing function of SATB1 in tumor progression. Semin Cancer Biol. 2013 Apr;23(2):72-9. doi: 10.1016/j.semcancer.2012.06.009. Epub 2012 Jul 4. http://www.ncbi.nlm.nih.gov/pubmed/2277161

Khidhir KG, Woodward DF, Farjo NP, Farjo BK, Tang ES, Wang JW, Picksley SM, Randall VA. The prostamide-related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias. FASEB J. 2013 Feb;27(2):557-67. doi: 10.1096/fj.12-218156. Epub 2012 Oct 26. http://www.ncbi.nlm.nih.gov/pubmed/2310498

Weiß N, Stegemann A, Elsayed MA, Schallreuter KU, Luger TA, Loser K, Metze D, Weishaupt C, Böhm M Inhibition of the Prohormone Convertase Subtilisin-Kexin Isoenzyme-1 Induces Apoptosis in Human Melanoma Cells. J Invest Dermatol. 2013 Jun 27. doi: 10.1038/jid.2013.282. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/2388424

Krüger C, Schallreuter KU. Cumulative life course impairment in vitiligo. Curr Probl Dermatol. 2013;44:102-17. doi: 10.1159/000350010. Epub 2013 May 24. http://www.ncbi.nlm.nih.gov/pubmed/2379681

Krüger C, Panske A, Schallreuter KU. Disease-related behavioral patterns and experiences affect quality of life in children and adolescents with vitiligo. Int J Dermatol. 2013 May 21. doi: 10.1111/j.1365-4632.2012.05656.x. [Epub ahead of print] http://www.ncbi.nlm.nih.gov/pubmed/2369240

Schallreuter KU, Salem MA, Holtz S, Panske A. Basic evidence for epidermal H2O2/ONOO--mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS. FASEB J. 2013 Apr 29. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/2362986

Soon CF, Khaghani SA, Youseffi M, Nayan N, Saim H, Britland S, Blagden N, Denyer MC. Interfacial study of cell adhesion to liquid crystals using widefield surface plasmon resonance microscopy. Colloids Surf B Biointerfaces. 2013 Oct 1;110:156-62. doi: 10.1016/j.colsurfb.2013.04.012. Epub 2013 Apr 25. http://www.ncbi.nlm.nih.gov/pubmed/23711786

Kirkby NS, Zaiss AK, Urquhart P, Jiao J, Austin PJ, Al-Yamani M, Lundberg MH, Mackenzie LS, Warner TD, Nicolaou A, Herschman HR, Mitchell JA. LC-MS/MS Confirms That COX-1 Drives Vascular Prostacyclin Whilst Gene Expression Pattern Reveals Non-Vascular Sites of COX-2 Expression. PLoS One. 2013 Jul 9;8(7):e69524. doi: 10.1371/journal.pone.0069524. Print 2013. http://www.ncbi.nlm.nih.gov/pubmed/2387497

Kirkby NS, Chan MV, Lundberg MH, Massey KA, Edmands WM, Mackenzie LS, Holmes E, Nicolaou A, Warner TD, Mitchell JA. Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test. FASEB J. 2013 Jun 21. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/23792301

Pergolizzi J, Ahlbeck K, Aldington D, Alon E, Coluzzi F, Dahan A, Huygen F, Kocot-K¿pska M, Mangas AC, Mavrocordatos P, Morlion B, Müller-Schwefe G, Nicolaou A, Pérez Hernández C, Sichère P, Schäfer M, Varrassi G.The development of chronic pain: physiological CHANGE necessitates a multidisciplinary approach to treatment. Curr Med Res Opin. 2013 Jul 3. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/23786498

Murphy SA, Nicolaou A. Lipidomics applications in health, disease and nutrition research. Mol Nutr Food Res. 2013 Jun 3. doi: 10.1002/mnfr.201200863. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/23729171

Sinn M, Nicolaou A, Gebauer B, Podrabsky P, Seehofer D, Ricke J, Dörken B, Riess H, Hildebrandt B. Hepatic Arterial Infusion with Oxaliplatin and 5-FU/Folinic Acid for Advanced Biliary Tract Cancer: A Phase II Study. Dig Dis Sci. 2013 Mar 24. [Epub ahead of print].http://www.ncbi.nlm.nih.gov/pubmed/23525734

MacCallum SF, Groves MJ, James J, Murray K, Appleyard V, Prescott AR, Drbal AA, Nicolaou A, Cunningham J, Haydock S, Ganley IG, Westwood NJ, Coates PJ, Lain S, Tauro S. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Sci Rep. 2013;3:1275. doi: 10.1038/srep01275.  http://www.ncbi.nlm.nih.gov/pubmed/23429453

Pilkington SM, Massey KA, Bennett SP, Al-Aasswad NM, Roshdy K, Gibbs NK, Friedmann PS, Nicolaou A, Rhodes LE. Randomized controlled trial of oral omega-3 PUFA in solar-simulated radiation-induced suppression of human cutaneous immune responses. Am J Clin Nutr. 2013 Mar;97(3):646-52. doi: 10.3945/ajcn.112.049494. Epub 2013 Jan 30.  http://www.ncbi.nlm.nih.gov/pubmed/23364005

Rhodes LE, Darby G, Massey KA, Clarke KA, Dew TP, Farrar MD, Bennett S, Watson RE, Williamson G, Nicolaou A.  Oral green tea catechin metabolites are incorporated into human skin and protect against UV radiation-induced cutaneous inflammation in association with reduced production of pro-inflammatory eicosanoid 12-hydroxyeicosatetraenoic acid. Br J Nutr. 2013 Jan 28:1-10. [Epub ahead of print]. http://www.ncbi.nlm.nih.gov/pubmed/23351338

Poloso NJ, Urquhart P, Nicolaou A, Wang J, Woodward DF. PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4). Mol Immunol. 2013 Jul;54(3-4):284-95. doi: 10.1016/j.molimm.2012.12.010. Epub 2013 Jan 20.  http://www.ncbi.nlm.nih.gov/pubmed/23337716

Wittmann M, Helliwell PS. Phosphodiesterase 4 inhibition in the treatment of psoriasis, psoriatic arthritis and other chronic inflammatory diseases. Dermatol Ther (Heidelb). 2013 Apr 27;3(1):1-15. doi: 10.1007/s13555-013-0023-0. Print 2013 Jun.  http://www.ncbi.nlm.nih.gov/pubmed/23888251

Seltmann J, Werfel T, Wittmann M. Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation.  Exp Dermatol. 2013 Feb;22(2):102-7. doi: 10.1111/exd.12076.  http://www.ncbi.nlm.nih.gov/pubmed/23362867

Jans R, Mottram L, Johnson DL, Brown AM, Sikkink S, Ross K, Reynolds NJ. Lysophosphatidic acid promotes cell migration through STIM1- and Orai1-mediated Ca2+(i) mobilization and NFAT2 activation. J Invest Dermatol. 2013 Mar;133(3):793-802. doi: 10.1038/jid.2012.370. Epub 2012 Oct 25. http://www.ncbi.nlm.nih.gov/pubmed/23096711

Schallreuter KU. Q10-triggered facial vitiligo. Br J Dermatol. 2013 Dec;169(6):1333-6. doi: 10.1111/bjd.12587. PMID: 23952052 


(2012)

Top

Massey KA, Nicolaou A. Lipidomics of oxidized polyunsaturated fatty acids. Free Radic Biol Med. 2012 Aug 19. http://www.ncbi.nlm.nih.gov/pubmed/22940496

Alase A, Seltmann J, Werfel T, Wittmann M. IL-33 Modulates the Expression of Human Beta Defensin 2 in Human Primary Keratinocytes and may influence the susceptibility to bacterial superinfection in acute atopic dermatitis. Br J Dermatol. 2012 Jul 14. doi: 10.1111/j.1365-2133.2012.11140.x. http://www.ncbi.nlm.nih.gov/pubmed/22803572

Grant CA, Twigg PC, Tobin DJ. Static and dynamic nanomechanical properties of human skin tissue using atomic force microscopy: Effect of scarring in the upper dermis. Acta Biomater. 2012 Jul 6.  http://www.ncbi.nlm.nih.gov/pubmed/22771457

Botchkarev VA, Gdula MR, Mardaryev AN, Sharov AA, Fessing MY. Epigenetic Regulation of Gene Expression in Keratinocytes. J Invest Dermatol. 2012 Jul 5. doi: 10.1038/jid.2012.182. http://www.ncbi.nlm.nih.gov/pubmed/22763788 

Britland S, Ross-Smith O, Jamil H, Smith AG, Vowden K, Vowden P. The lactate conundrum in wound healing: Clinical and experimental findings indicate the requirement for a rapid point-of-care diagnostic. Biotechnol Prog. 2012 Jul;28(4):917-24. doi: 10.1002/btpr.1561.http://www.ncbi.nlm.nih.gov/pubmed/22581665

Nicolaou A. Eicosanoids in skin inflammation.Prostaglandins Leukot Essent Fatty Acids. 2012 Apr 20. http://www.ncbi.nlm.nih.gov/pubmed/22521864

Krüger C, Schallreuter KU. A review of the worldwide prevalence of vitiligo in children/adolescents and adults. Int J Dermatol. 2012 Mar 27. doi:10.1111/j.1365-4632.2011.05377.x. [Epub ahead of print] PubMed PMID: 22458952. http://www.ncbi.nlm.nih.gov/pubmed/22458952

Schallreuter KU, Salem MA, Gibbons NC, Maitland DJ, Marsch E, Elwary SM, Healey AR. Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: Epidermal H2O2/ONOO(-)-mediated stress in vitiligo hampers indoleamine 2,3-dioxygenase and aryl hydrocarbon receptor-mediated immune response signaling. FASEB J. 2012 Jun;26(6):2471-85. http://www.ncbi.nlm.nih.gov/pubmed/22415306 

Schallreuter KU, Salem MA, Gibbons NC, Martinez A, Slominski R, Lüdemann J, Rokos H. Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels. FASEB J. 2012 Jun;26(6):2457-70.http://www.ncbi.nlm.nih.gov/pubmed/22415302

Botchkareva NV. MicroRNA/mRNA regulatory networks in the control of skin development and regeneration. Cell Cycle. 2012 Feb 1;11(3):468-74. http://www.ncbi.nlm.nih.gov/pubmed/22262186 

Nicolaou A, Masoodi M, Gledhill K, Haylett AK, Thody AJ, Tobin DJ, Rhodes LE. The eicosanoid response to high dose UVR exposure of individuals prone and resistant to sunburn. Photochem Photobiol Sci. 2012 Feb;11(2):371-80. http://www.ncbi.nlm.nih.gov/pubmed/22173231


(2011)

Top

 

Mardaryev AN, Meier N, Poterlowicz K, Sharov AA, Sharova TY, Ahmed MI, Rapisarda V, Lewis C, Fessing MY, Ruenger TM, Bhawan J, Werner S, Paus R, Botchkarev VA. Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury. Development. 2011 Nov;138(22):4843-52. http://www.ncbi.nlm.nih.gov/pubmed/22028024

Massey KA, Nicolaou A. Lipidomics of polyunsaturated-fatty-acid derived oxygenated metabolites. Biochem Soc Trans. 2011 Oct;39(5):1240-6. Review. http://www.ncbi.nlm.nih.gov/pubmed/21936796 

Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA. p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39. http://www.ncbi.nlm.nih.gov/pubmed/21930775

Nicolaou A, Pilkington SM, Rhodes LE. Ultraviolet-radiation induced skin inflammation: dissecting the role of bioactive lipids. Chem Phys Lipids. 2011 Sep;164(6):535-43. Epub 2011 Apr 15. Review. http://www.ncbi.nlm.nih.gov/pubmed/21524643

Britland S, Smith A, Finter W, Eagland D, Vowden K, Vowden P, Telford G, Brown A, Pritchard D. Recombinant Lucilia sericata chymotrypsin in a topical hydrogel formulation degrades human wound eschar ex vivo. Biotechnol Prog. 2011 May-Jun;27(3):870-4. doi: 10.1002/btpr.587. Epub 2011 Apr 20. PubMed PMID:21509949.http://www.ncbi.nlm.nih.gov/pubmed/21509949

Krüger C, Smythe JW, Spencer JD, Hasse S, Panske A, Chiuchiarelli G, Schallreuter KU. Significant immediate and long-term improvement in quality of life and disease coping in patients with vitiligo after group climatotherapy at the Dead Sea. Acta Derm Venereol. 2011 Mar;91(2):152-9. PubMed PMID: 21240455. http://www.ncbi.nlm.nih.gov/pubmed/21240455

Stephen Britland and Milli Hoyle. Transcriptional gene-silencing of kallikreins 5 and 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema. Biotechnology Progress. 2011 Oct 3. doi: 10.1002/btpr.736.

Ahmed MI, Mardaryev AN, Lewis CJ, Sharov AA, Botchkareva NV. MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes. J Cell Sci. 2011 Oct 15; 124(Pt 20):3399-404. http://www.ncbi.nlm.nih.gov/pubmed/21984808

Peters EM, Liezmann C, Spatz K, Daniltchenko M, Joachim R, Gimenez-Rivera A, Hendrix S, Botchkarev VA, Brandner JM, Klapp BF. Nerve growth factor partially recovers inflamed skin from stress-induced worsening in allergic inflammation. J Invest Dermatol. 2011 Mar;131(3):735-43. http://www.ncbi.nlm.nih.gov/pubmed/21085186

Sharma V, Singh SK, Anderson D, Tobin DJ, Dhawan A. Zinc oxide nanoparticle induced genotoxicity in primary human epidermal keratinocytes. J Nanosci Nanotechnol. 2011 May;11(5):3782-8. http://www.ncbi.nlm.nih.gov/pubmed/21780369

Baris OR, Klose A, Kloepper JE, Weiland D, Neuhaus JF, Schauen M, Wille A, Müller A, Merkwirth C, Langer T, Larsson NG, Krieg T, Tobin DJ, Paus R, Wiesner RJ. The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells. 2011 Sep;29(9):1459-68. doi: 10.1002/stem.695. http://www.ncbi.nlm.nih.gov/pubmed/21780252

Bengtsson CF, Olsen ME, Brandt LO, Bertelsen MF, Willerslev E, Tobin DJ, Wilson AS, Gilbert MT. DNA from keratinous tissue. Part I: Hair and nail. Ann Anat. 2011 Apr 5.  http://www.ncbi.nlm.nih.gov/pubmed/21530205

Fischer H, Szabo S, Scherz J, Jaeger K, Rossiter H, Buchberger M, Ghannadan M, Hermann M, Theussl HC, Tobin DJ, Wagner EF, Tschachler E, Eckhart L. Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails.  J Invest Dermatol. 2011 Jun;131(6):1208-15. http://www.ncbi.nlm.nih.gov/pubmed/21307874 

Slominski AT, Zmijewski MA, Zbytek B, Brozyna AA, Granese J, Pisarchik A, Szczesniewski A, Tobin DJ. Regulated proenkephalin expression in human skin and cultured skin cells. J Invest Dermatol. 2011 Mar;131(3):613-22. http://www.ncbi.nlm.nih.gov/pubmed/21191404

Kauser S, Westgate GE, Green MR, Tobin DJ. Human hair follicle and epidermal melanocytes exhibit striking differences in their aging profile which involves catalase. J Invest Dermatol. 2011 Apr;131(4):979-82.  http://www.ncbi.nlm.nih.gov/pubmed/21191398 

Tobin DJ. The cell biology of human hair follicle pigmentation. Pigment Cell Melanoma Res. 2011 Feb;24(1):75-88. http://www.ncbi.nlm.nih.gov/pubmed/21070612 

Tobin DJ. Ex vivo organ culture of human hair follicles: a model epithelial-neuroectodermal-mesenchymal interaction system. Methods Mol Biol. 2011;695:213-27. 

http://www.ncbi.nlm.nih.gov/pubmed/21042975


(2010)

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Singh SK, Kurfurst R, Nizard C, Schnebert S, Perrier E, Tobin DJ. Melanin transfer in human skin cells is mediated by filopodia--a model for homotypic and heterotypic lysosome-related organelle transfer. FASEB J. 2010 Oct;24(10):3756-69. http://www.ncbi.nlm.nih.gov/pubmed/20501793

Schallreuter KU, Salem MM, Hasse S, Rokos H. The redox - biochemistry of human hair pigmentation.  Pigment Cell Melanoma Res. 2010 Oct 19. doi: 10.1111/j.1755-148X.2010.00794.x. [Epub ahead of print]  http://www.ncbi.nlm.nih.gov/pubmed/20958953

Leung MC, Sutton CW, Fenton DA, Tobin DJ. Trichohyalin is a potential major autoantigen in human alopecia areata. J Proteome Res. 2010 Oct 1;9(10):5153-63. http://www.ncbi.nlm.nih.gov/pubmed/20722389

Sharov AA, Schroeder M, Sharova TY, Mardaryev AN, Peters EM, Tobin DJ, Botchkarev VA. Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation. J Invest Dermatol. 2010 Sep 30. [Epub ahead of print] No abstract available. 

Miranda BH, Tobin DJ, Sharpe DT, Randall VA. Intermediate hair follicles: a new more clinically relevant model for hair growth investigations. Br J Dermatol. 2010 Aug;163(2):287-95. Epub 2010 May 25. http://www.ncbi.nlm.nih.gov/pubmed/20500795

Masoodi M, Nicolaou A, Gledhill K, Rhodes LE, Tobin DJ, Thody AJ. Prostaglandin D(2) production in FM55 melanoma cells is regulated by alpha-melanocyte-stimulating hormone and is not related to melanin production. Exp Dermatol. 2010 Aug;19(8):751-3.  http://www.ncbi.nlm.nih.gov/pubmed/20482620 

Kelly L, Grehan B, Chiesa AD, O'Mara SM, Downer E, Sahyoun G, Massey KA, Nicolaou A, Lynch MA. The polyunsaturated fatty acids, EPA and DPA exert a protective effect in the hippocampus of the aged rat. Neurobiol Aging. 2010 Jun 4. http://www.ncbi.nlm.nih.gov/pubmed/20570403

Hoogduijn MJ, Popp F, Verbeek R, Masoodi M, Nicolaou A, Baan C, Dahlke MH. The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy. Int Immunopharmacol. 2010 Jul 7. http://www.ncbi.nlm.nih.gov/pubmed/20619384 

Gledhill K, Rhodes LE, Brownrigg M, Haylett AK, Masoodi M, Thody AJ, Nicolaou A, Tobin DJ. Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner. Pigment Cell Melanoma Res. 2010 Jun;23(3):394-403. Epub 2010 Mar 17. http://www.ncbi.nlm.nih.gov/pubmed/20236442

Higgins CA, Richardson GD, Ferdinando D, Westgate GE, Jahoda CA. Modelling the hair follicle dermal papilla using spheroid cell cultures. Exp Dermatol. 2010 Jun;19(6):546-8. Epub 2010 Apr 20. http://www.ncbi.nlm.nih.gov/pubmed/20456497

Mardaryev AN, Ahmed MI, Vlahov NV, Fessing MY, Gill JH, Sharov AA, Botchkareva NV. Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle. FASEB J. 2010 Oct;24(10):3869-81 http://www.ncbi.nlm.nih.gov/pubmed/20522784

Schallreuter KU, Salem MM. [Vitiligo : What is new?] Hautarzt. 2010 Jun 13. German. http://www.ncbi.nlm.nih.gov/pubmed/20549479 

Singh SK, Kurfurst R, Nizard C, Schnebert S, Perrier E, Tobin DJ. Melanin transfer in human skin cells is mediated by filopodia - a model for homotypic and heterotypic lysosome-related organelle transfer. FASEB J. 2010 Oct;24(10):3756-69. Epub 2010 May 25. http://www.ncbi.nlm.nih.gov/pubmed/20501793

Massey KA, Snelling AM, Nicolaou A. Quantitative analysis of surfactant deposits on human skin by liquid chromatography/electrospray ionisation tandem mass spectrometry. Rapid Commun Mass Spectrom. 2010 May 15;24(9):1371-6. http://www.ncbi.nlm.nih.gov/pubmed/20391611 

Lyubimova A, Garber JJ, Upadhyay G, Sharov A, Anastasoaie F, Yajnik V, Cotsarelis G, Dotto GP, Botchkarev V, Snapper SB. Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice. J Clin Invest. 2010 Feb 1;120(2):446-56. doi: 10.1172/JCI36478. Epub 2010 Jan 11. http://www.ncbi.nlm.nih.gov/pubmed/20071778

Fessing MY, Atoyan R, Shander B, Mardaryev AN, Botchkarev VV Jr, Poterlowicz K, Peng Y, Efimova T, Botchkarev VA. BMP signaling induces cell-type-specific changes in gene expression programs of human keratinocytes and fibroblasts. J Invest Dermatol. 2010 Feb;130(2):398-404. Epub 2009 Aug 27. http://www.ncbi.nlm.nih.gov/pubmed/19710687


(2009)   

Top

Salem MM, Shalbaf M, Gibbons NC, Chavan B, Thornton JM, Schallreuter KU.

Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage.

FASEB J. 2009 Nov;23(11):3790-807. Epub 2009 Jul 29.
http://www.ncbi.nlm.nih.gov/pubmed/19641144


Rhodes LE, Gledhill K, Masoodi M, Haylett AK, Brownrigg M, Thody AJ, Tobin DJ, Nicolaou A.

The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases.

FASEB J. 2009 Nov;23(11):3947-56.    
http://www.ncbi.nlm.nih.gov/pubmed/19584301


Stevenson S, Sharpe DT, Thornton MJ.

Effects of oestrogen agonists on human dermal fibroblasts in an in vitro wounding assay.

Exp Dermatol. 2009 Nov;18(11):988-90.
http://www.ncbi.nlm.nih.gov/pubmed/19469894


Vafaee T, Rokos H, Salem MM, Schallreuter KU.

In vivo and in vitro evidence for epidermal HO-mediated oxidative stress in piebaldism.

Exp Dermatol. 2009 Sep 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/19758321


Plonka PM, Passeron T, Brenner M, Tobin DJ, Shibahara S, Thomas A, Slominski A, Kadekaro AL, Hershkovitz D, Peters E, Nordlund JJ, Abdel-Malek Z, Takeda K, Paus R, Ortonne JP, Hearing VJ, Schallreuter KU.

What are melanocytes really doing all day long...?

Exp Dermatol. 2009 Sep;18(9):799-819. Epub 2009 Jul 30. Review.

Erratum in: Exp Dermatol. 2009 Dec;18(12):1096.
http://www.ncbi.nlm.nih.gov/pubmed/19659579


Atoyan R, Shander D, Botchkareva NV.

Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.

J Invest Dermatol. 2009 Sep;129(9):2312-5. Epub 2009 Mar 12. No abstract available.


Sharov AA, Mardaryev AN, Sharova TY, Grachtchouk M, Atoyan R, Byers HR, Seykora JT, Overbeek P, Dlugosz A, Botchkarev VA.

Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways.

Am J Pathol. 2009 Sep;175(3):1303-14. Epub 2009 Aug 21.
http://www.ncbi.nlm.nih.gov/pubmed/19700758


Higgins CA, Richardson GD, Westgate GE, Jahoda CA.

Exogen involves gradual release of the hair club fibre in the vibrissa follicle model.

Exp Dermatol. 2009 Sep;18(9):793-5.   
http://www.ncbi.nlm.nih.gov/pubmed/19695019


Higgins CA, Westgate GE, Jahoda CA.

From telogen to exogen: mechanisms underlying formation and subsequent loss of the hair club fiber.

J Invest Dermatol. 2009 Sep;129(9):2100-8. Epub 2009 Apr 2. Review.
http://www.ncbi.nlm.nih.gov/pubmed/19340011


Schallreuter KU, Hasse S, Rokos H, Chavan B, Shalbaf M, Spencer JD, Wood JM.

Cholesterol regulates melanogenesis in human epidermal melanocytes and melanoma cells.

Exp Dermatol. 2009 Aug;18(8):680-8. Epub 2009 Mar 7.
http://www.ncbi.nlm.nih.gov/pubmed/19469904


Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, Hasse S, Thornton MJ, Shalbaf M, Paus R, Schallreuter KU.

Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair.

FASEB J. 2009 Jul;23(7):2065-75. Epub 2009 Feb 23.
http://www.ncbi.nlm.nih.gov/pubmed/19237503


Hulse WL, Forbes RT, Bonner MC, Getrost M.

The characterization and comparison of spray-dried mannitol samples.

Drug Dev Ind Pharm. 2009 Jun;35(6):712-8.
http://www.ncbi.nlm.nih.gov/pubmed/19514986


Spencer JD, Schallreuter KU.

Regulation of pigmentation in human epidermal melanocytes by functional high-affinity beta-melanocyte-stimulating hormone/melanocortin-4 receptor signaling.

Endocrinology. 2009 Mar;150(3):1250-8. Epub 2008 Oct 30.
http://www.ncbi.nlm.nih.gov/pubmed/18974267


Gurtovenko AA, Anwar J.

Interaction of ethanol with biological membranes: the formation of non-bilayer structures within the membrane interior and their significance.

J Phys Chem B. 2009 Feb 19;113(7):1983-92.
http://www.ncbi.nlm.nih.gov/pubmed/19199697


Chavan B, Beazley W, Wood JM, Rokos H, Ichinose H, Schallreuter KU.

H2O2 increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo.

J Inherit Metab Dis. 2009 Feb;32(1):86-94. Epub 2008 Dec 22.
http://www.ncbi.nlm.nih.gov/pubmed/19101819


Nicolaou A, Masoodi M, Mir A.

Lipidomic analysis of prostanoids by liquid chromatography-electrospray tandem mass spectrometry.

Methods Mol Biol. 2009;579:271-86.    
http://www.ncbi.nlm.nih.gov/pubmed/19763481

Books

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Hair in Toxicology: An Important Bio-Monitor

Royal Society of Chemistry

Desmond John Tobin (Editor)

ISBN: 978-0-85404-587-7

Copyright: 2005

Format: Hardback

Extent: 355

http://www.rsc.org/shop/books/2005/9780854045877.asp

Hair in Toxicology: An Important Biomonitor is the first book of its kind devoted exclusively to in-depth analysis of the hair shaft as an important tool for a diverse range of scientific investigations. This authoritative book combines contributions from experts in academic, governmental and industrial environments, to provide a unique, comprehensive look at:

  • Why hair can serve as an invaluable bio-resource in toxicology, with up-to-date reviews on hair growth, hair fibre formation and hair pigmentation
  • Information (including regulatory details) on the exposure of hair (and by extension the body) to drug and non-drug chemicals and pollutants
  • Toxicological issues relevant to the use of hair products (including colourants, shampoos and depilatories)
  • The ability of hair to capture information on personal identity, chemical exposure, and environmental interactions
  • How hair can provide an understanding of human life from archaeological and historical perspectives
  • Future direction in the use of hair in toxicology

Hair Loss Disorders in Domestic Animals

Lars Mecklenburg (Editor), Monika Linek (Editor), Desmond J. Tobin (Editor)

ISBN: 978-0-8138-1082-9

Hardcover

288 pages

July 2009, Wiley-Blackwell

http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0813810825.html

Hair Loss Disorders in Domestic Animals is an in-depth reference on the pathomechanisms and clinical approaches of all skin diseases in domestic animals that have hair loss as the predominant clinical feature. It presents both basic and clinically-relevant knowledge on alopecic disease in animals. This text is a one-of-a-kind resource providing cutting-edge coverage of the physiology and pathology of hair follicles. Disease-specific chapters include: a detailed description of the disease entity, etiology, pathogenesis, clinical and histopathological diagnosis and treatment modalities.


Aging Hair

Ralph M Trüeb (Editor), Desmond J Tobin, (Editor)

ISBN: 978-3-642-02635-5

Hardcover

288 pages

April 2010

http://www.springer.com/medicine/dermatology/book/978-3-642-02635-5

The scalp and hair are subject to both intrinsic or physiologic aging and extrinsic or premature aging caused by external factors. This comprehensive and reader-friendly book offers an up-to-date overview on all aspects of hair aging, including in particular the two main streams of interest: the aesthetic problem, which relates to everything that happens outside the skin, and the biologic problem, which concerns the "secret life" of the hair follicle in the depth of the skin. Internationally recognized experts provide detailed contributions on the biologic basis of hair aging and current concepts for its diagnosis, treatment, and prevention. The intrinsic and extrinsic modulating factors for hair growth and pigmentation are explained and future directions for therapeutic intervention are examined. In summary, this unique book offers valuable insights into hair aging and guidance on its treatment; it will prove invaluable both to dermatologists and to other interested physicians and basic scientists.

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