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Predicting How Tablets Crush

Case Study: Modelling the crushing behaviour or pharmaceutical tablets

One way to improve the design of pharmaceutical tablets is to understand how they'll break down under physical pressure. In this study, working with another University department, we created a computer simulation to model how different sizes and shapes of tablet behave when crushed.

Aim

To develop a computer based simulation platform to study the crushing behaviour of Pharmaceutical Tablets.

Client

Institute of Pharmaceutical Innovation, University of Bradford.

Project

Using mathematical modelling we have develop a computer platform that can predict the crushing behaviour of a typical pharmaceutical tablet. The computer model has been tested and validated using real data supplied by the Institute of Pharmaceutical Innovation.

Results

The platform enables to predict the crushing behaviour of tablets and would enable better design of tablets