researcher

Farshid Sefat

Lecturer in Medical Engineering

RoleLecturer in Medical Engineering
Faculty/Dept/SchoolFaculty of Engineering & Informatics / Biomedical and Electronics Engineering
EmailF.Sefat1@bradford.ac.uk
Telephone+441274233679

Biography

Dr Farshid Sefat is Assistant Professor (Lecturer) in Biomedical and Electronic Engineering Department at the University of Bradford (UK) and previously was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and also a Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in the area of cornea tissue engineering. He received his Ph.D. (2011) and BEng. (2005) degrees from University of Bradford (UK) both in Biomedical Engineering mainly focus on bone cell engineering. He also obtained his MSc. (2006) in Cell and Tissue Engineering from Keele University (UK).    

His research is based on developing biomaterials to control cellular behaviour with particular emphasis in developing engineered materials for various tissue engineering applications.  He is an author on >100 peer-reviewed journal articles, editorials and review papers and >30 book chapters/edited books. He is on the editorial boards and reviewer of >30 numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, MDPI, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C, Journal of Biomechanics and many more.  

Research

Key areas of research interest: 1. Skin, Hair, Breast and Cornea Tissue Engineering 2. Oral/Dental Tissue Engineering 3. Bone and Cartilage Cell Engineering 4. Dental Biomaterials 5. Biomaterials Fabrication & Characterization 6. Effect of Mechanical Stimulation on Bone Cell Behaviour 7. Effects of Growth Factors on Cell Behaviour (Cell Signalling) 8. Synthesis of Antibacterial Peptides for Dental Implant Modification Current research areas include: 1. Optimisation of layer-by-layer 3D scaffold for dermal wound healing 2. Fabrication and characterisation of biodegradable scaffolds for cornea tissue engineering 3. Cell signalling pathways of Transforming Growth Factor Beta (TGF-β isomers) 4. Investigating breast cancer behaviour using tissue engineering scaffolds 5. Electrospun nanofibers for vascular tissue engineering

Professional activities

  • - BSc (Hons)
  • - Beng (Hons)
  • - MSc
  • - PhD
  • 01-JAN-18: - MeDe UK Best Video Award 
  • 01-JAN-13: - Best Paper award for 4th International Conference on Biotech
  • 01-JAN-11: - Best Paper award for 13th Annual White Rose Meeting, Biomate
  • 01-JAN-10: - Best paper award of World Congress of Engineering (WCE 2010)
  • 01-JAN-10: - Best paper award of World Congress of Engineering (WCE 2010)
  • 01-JAN-09: - Best paper award of World Congress of Engineering (WCE 2009)
  • 01-JAN-09: - Best paper award of World Congress of Engineering (WCE 2009)

Publications

Peer Reviewed Journal
TitleBiosynthetic PCL-graft-collagen bulk material for tissue engineering applications (2017)
AuthorsGentile P.;McColgan-Bannon K.;Gianone N.;Sefat F.;Dalgarno K.;Ferreira A.
JournalMaterials
DOI10.3390/ma10070693
 
TitleComparison of biophysical properties characterized for microtissues cultured using microencapsulation and liquid crystal based 3D cell culture techniques (2018)
AuthorsSoon C.;Tee K.;Wong S.;Nayan N.;Sargunan Sundra;Ahmad M.;Sefat F.;Sultana N.;Youseffi M.
JournalCytotechnology
DOI10.1007/s10616-017-0168-2
 
TitleSynthesis of Indolo[3,2-b]carbazoles via an Anomeric-Based Oxidation Process: A Combined Experimental and Computational Strategy (2018)
AuthorsZolfigol M.;Khazaei A.;Karimitabar F.;Hamidi M.;Maleki F.;Aghabarari B.;Sefat F.;Mozafari M.
JournalJournal of Heterocyclic Chemistry
DOI10.1002/jhet.3077
 
TitleAligned electrospun cellulose scaffolds coated with rhBMP-2 for both in vitro and in vivo bone tissue engineering. (2019)
AuthorsZhang X;Wang C;Liao M;Dai L;Tang Y;Zhang H;Coates P;Sefat F;Zheng L;Song J;Zheng Z;Zhao D;Yang M;Zhang W;Ji P;
JournalCarbohydrate Polymers
DOI10.1016/j.carbpol.2019.02.038
 
TitleImaging via widefield surface plasmon resonance microscope for studying bone cell interactions with micropatterned ECM proteins (2011)
AuthorsSefat F.;Denyer M.;Youseffi M.
JournalJournal of Microscopy
DOI10.1111/j.1365-2818.2010.03430.x
 
TitleSimplifying corneal surface regeneration using a biodegradable synthetic membrane and limbal tissue explants. (2013)
AuthorsDeshpande P;Ramachandran C;Sefat F;Mariappan I;Johnson C;McKean R;Hannah M;Sangwan VS;Claeyssens F;Ryan AJ;MacNeil S;
JournalBiomaterials
DOI10.1016/j.biomaterials.2013.03.064
 
TitleShape-controlled silver NPs for shape-dependent biological activities (2017)
AuthorsSadeghi F.;Yazdanpanah A.;Abrishamkar A.;Moztarzadeh F.;Ramedani A.;Pouraghaie S.;Shirinzadeh H.;Samadikuchaksaraei A.;Chauhan N.;Hopkinson L.;Sefat F.;Mozafari M.
JournalMicro and Nano Letters
DOI10.1049/mnl.2016.0804
 
TitleFabrication and Characterisations of Hydrogels for Cartilage Repair (2017)
Authors11. Kaur, P., Khaghani, S.A., Oluwadamilola, A., Khurshid, Z., Zafar, M.S., Mozafari, M., Youseffi, M and Sefat, F
JournalJournal of tissue engineering and regenerative medicine
 
TitleProduction, Sterilisation and Storage of Biodegradable Electrospun PLGA Membranes for Delivery of Limbal Stem Cells to the Cornea (2013)
AuthorsSefat, F., McKean, R., Deshpande, P., Ramachandran, C., Hill, C., Sangwan, V., Ryan, A. and MacNeil, S.
JournalProcedia Engineering
 
TitleThe Effect of WIN55, 212-2 on Protein S100, Matrix Metalloproteinase-2 and Nitric Oxide Expression of Chondrocyte Monolayer (2017)
AuthorsAbdeldayem A, Youseffi M, Sefat F, Genedy M, Abdul Jamil, M.M., Javid F.
JournalJournal of Biomedical Engineering
 
TitleTransplantation of adipose tissue-derived stem cells into brain through cerebrospinal fluid in rat models: Protocol development and initial outcome data. (2018)
AuthorsAmini N;Vousooghi N;Alizade A;Ramezani S;Joghataei MT;Milan PB;Mehrabi S;Ababzadeh S;Sefat F;Mozafari M;
JournalCurrent Stem Cell Research and Therapy
DOI10.2174/1574888X13666180720112322
 
TitleIncreasing elastin fibre production in a tissue engineered mesh for pelvic floor surgery (2014)
AuthorsOsman, N.; Roman, S.; Sefat, Farshid; Bullock, A.J.; Chapple, C.R.
 
TitleEffect of transforming growth factor-β on up/down regulation of integrin-β1 in primary chondrocyte culture (2016)
AuthorsKhaghani, Seyed A.; Sefat, Farshid; Youseffi, Mansour; Rehman, R.; Soon, Chin Fhong; Akbarova, G.
 
TitleCombination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration (2014)
AuthorsOrtega, Í.; Sefat, Farshid; Deshpande, P.; Paterson, T.; Ramachandran, C.; Ryan, A.J.; MacNeil, S.; Claeyssens, F.
 
TitleDevelopment of a Basement Membrane Substitute Incorporated Into an Electrospun Scaffold for 3D Skin Tissue Engineering (2014)
AuthorsBye, F.J.; Bullock, A.J.; Singh, R.; Sefat, Farshid; Roman, S.; MacNeil, S.
 
TitleRocking Media Over Ex Vivo Corneas Improves This Model and Allows the Study of the Effect of Proinflammatory Cytokines on Wound Healing (2015)
AuthorsDeshpande, P.; Ortega, Í.; Sefat, Farshid; Sangwan, V.S.; Green, N.H.; Claeyssens, F.; MacNeil, S.
 
TitleRapid creation of skin substitutes from human skin cells and biomimetic nanofibers for acute full-thickness wound repair (2015)
AuthorsMahjour, S.B.; Fu, X.; Yang, X.; Fong, J.; Sefat, Farshid; Wang, H.
 
TitleTransforming Growth Factor Beta (TGF-β): Natural Curing Agents for Repair (2014)
AuthorsSefat, Farshid
 
TitleDental Applications of Nanodiamonds (2016)
AuthorsNajeeb, S.; Khurshid, Z.; Agwan, A.S.; Zafar, M.S.; Alrahabi, M.; Bin Qasim, S.; Sefat, Farshid
 
TitleImpact of packing and processing technique on mechanical properties of acrylic denture base materials (2015)
AuthorsNejatian, T.; Sefat, Farshid; Johnson, T.
 
TitleImproved cell infiltration of electrospun nanofiber mats for layered tissue constructs (2016)
AuthorsMahjour, S.B.; Sefat, Farshid; Polunin, Y.; Wang, L.; Wang, H.
 
TitleEffect of Transforming Growth Factor-β3 on mono and multilayer chondrocytes (2016)
AuthorsSefat, Farshid; Youseffi, Mansour; Khaghani, Seyed A.; Soon, Chin Fhong; Javid, Farideh A.
 
TitleHistatin peptides: Pharmacological functions and their applications in dentistry (2016)
AuthorsKhurshid, Z.; Najeeb, S.; Mali, M.; Moin, S.F.; Raza, S.Q.; Zohaib, S.; Sefat, Farshid; Zafar, M.S.
 
TitlePotential of electrospun nanofibers for biomedical and dental applications (2016)
AuthorsZafar, M.S.; Najeeb, S.; Khurshid, Z.; Vazirzadeh, M.; Zohaib, S.; Najeeb, B.; Sefat, Farshid
 
TitleEffects of different transforming growth factor beta (TGF-β) isomers on wound closure of bone cell monolayers (2014)
AuthorsSefat, Farshid; Denyer, Morgan C.T.; Youseffi, Mansour
 
TitleTransforming growth factor beta (TGF-β) isomers influence cell detachment of MG-63 bone cells (2015)
AuthorsSefat, Farshid; Khaghani, Seyed A.; Nejatian, T.; Genedy, Mohamed A.; Abdeldayem, Ali I.A.; Moghaddam, Z.S.; Denyer, Morgan C.T.; Youseffi, Mansour